Management of alopecia in oncologic treatment patients

Main Article Content

Karine Corcione Turke
Jose Roberto Fraga Neto
Deli Brito de Oliveira
Laissa Arruda Pinto
Jean Schoueri
Vanessa Salzano
Dolores Gonzalez Fabra

Abstract

Introduction: The treatment of cancer has been evolving every day. However, adverse effects such as dermatological changes have a great psychosocial impact on cancer patients. One dermatological change is alopecia, characterized by loss of eyebrow and scalp strands. Case report: Two cases of patients undergoing chemotherapy with partial and total alopecia were reported. Both were treated with Minoxidil, which was topically used, with complete repilation after three months. No adverse effects observed. Conclusion: Minoxidil topical lotion has proven to be an effective and safe method to treat partial and total alopecia in patients still undergoing cancer treatment.

Downloads

Download data is not yet available.

Article Details

How to Cite
Turke, K. C., Fraga Neto, J. R., Oliveira, D. B. de, Pinto, L. A., Schoueri, J., Salzano, V., & Fabra, D. G. (2019). Management of alopecia in oncologic treatment patients. ABCS Health Sciences, 44(3). https://doi.org/10.7322/abcshs.v44i3.1395
Section
Reports

References

Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, et al. Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2014;136:E359-86. https://doi.org/10.1002/ijc.29210

Fabra DG, Kayo AP, Leal ARO, Salzano V, Guglielmino F. Alterações dermatológicas em pacientes oncológicos- adultos e crianças. Arq Bras Ciên Saúde. 2009;34(2):87-93. https://dx.doi.org/10.7322/abcs.v34i2.132

Cubero DIG, Abdalla BMZ, Schoueri J, Lopes FI, Turke KC, Guzman J, et al. Cutaneous side effects of molecularly targeted therapies for the treatment of solid tumors. Drugs in Context. 2018;7:212516. https://dx.doi.org/10.7573/dic.212516

Choi EK, Kim IR, Chang O, Kang D, Nam SJ, Lee JE, et al. Impact of chemotherapy-induced alopecia distress on body image, psychosocial well-being and depression in breast cancer patients. Psychooncology. 2014;23(10):1103-10. https://dx.doi.org/10.1002/pon.3531

Freites-Martinez A, Shapiro J, Chan D, Fornier M, Modi S, Gajria D, et al. Endocrine therapy-induced alopecia in patients with breast cancer. JAMA Dermatol. 2018;154(6):670-5. https://dx.doi.org/10.1001/jamadermatol.2018.0454

Fabra DG, Salzano V, Guglielnino F, Kayo AP. Impacto do ambuatório de reabilitação dermatocosmiátrica na qualidade de vida dos pacientes oncológicos da Faculdade de Medicina do ABC. Arq Bras Ciên Saúde. 2010:35(2):89-94. https://dx.doi.org/10.7322/abcs.v35i2.92

Trueb RM. Chemotherapy-induced alopecia. Semin Cutan Med Surg. 2009;28:11-14. https://dx.doi.org/10.1016/j.sder.2008.12.001

Grevelman EG, Breed WPM. Prevention of chemotherapy- induced hair loss by scalp cooling. Ann Oncol. 2005;16(3):352-8. https://dx.doi.org/10.1093/annonc/mdi088

Shin H, Jo SJ, Kim DH, Kwon O, Myung SK. Efficacy of interventions for prevention of chemotherapy-induced alopecia: a systematic reviwe and meta-analysis. Int J Cancer. 2015;136(5):E442-54. https://dx.doi.org/10.1002/ijc.29115

Barbareschi M. The use of minoxidil in the treatment of male and female androgenetic alopecia: a story of more than 30 year. G Ital Dermatol Venereol. 2018;153(1):102-6. https://dx.doi.org/10.23736/S0392-0488.17.05781-9

Rey MCW, Bonamigo RR. Tratamento de alopecia areata. Med Cutánea Iber Lat Am. 2006;34(2):49-52.

Messenger AG, Rundegren J. Minoxidil: mechanisms of action on hair growth. Br J Dermatol. 2004;150(2):186-94.

Headington JT. Hair follicle biology and topical minoxidil: possible mechanisms of action. Dermatologica. 1987;175(2):19-22. https://dx.doi.org/10.1159/000248894

Lucky AW, Piacquadio DJ, Ditre CM, Dunlap F, Kantor I, Pandya AG, et al. A randomized, placebo-controlled trial of 5% and 2% topical minoxidil solutions in the treatment of female pattern hair loss. J Am Acad Dermatol. 2004;50(4):541-53. https://dx.doi.org/10.1016/j.jaad.2003.06.014

Rossi A, Cantisani C, Melis L, Iorio A, Scali E, Calvieri S. Minoxidil use in dermatology, side effects and recent patents. Recent Pat inflamm Allergy Drug Discov. 2012;6(2):130-6. https://dx.doi.org/10.2174/187221312800166859