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Introduction: The growth of distance education (DE) in Brazil has been increasingly intense, including in health courses. Objective: To do a comparative analysis between the modalities about assessment of activity and academic performance. “Scavenger Hunt” was developed in Distance Learning (DL) mode in 2012, called “Virtual Scavenger Hunt”. Methods: The “Scavenger Hunt” was applied in DL mode in the first 2012 semester (n=40) and face‑to‑face in the second semester (n=42). The class was divided into two teams, for the first time the teams formulated tasks and the second time the tasks were exchanged between them. The students answered a final discipline assessment survey, considering Methodology, Collateral, Tasks and Considerations. Yet was assessed the academic performance between the two modes. Results: “Scavenger Hunt”, as the Methodology and the Task was a significant difference, with a preference for the face‑to‑face kind. As for the comments of the students, the use of synchronous Forum as a means of interaction is innovative, but can cause confusion and slow to update, hindering the interaction and dynamism of activity. On the other hand, it makes the Class participation higher because DL reduces exposure of the student. There was a better academic performance, on average, in the face‑to‑face mode. Conclusion: The educational games promotes increasing students’ attention and concentration because of the competition, so the interaction tool “Virtual Scavenger Hunt” should be interactive and dynamic, as well as in the face‑to‑face class.
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